"Nine Questions About Antihypertensive Medications, Are You Aware?"

Nowadays, many elderly people suffer from hypertension and rely on antihypertensive medications to maintain stable blood pressure. With numerous antihypertensive drugs available in clinical practice, which one is truly effective? How should one choose an antihypertensive medication? Do these medications have side effects? These are common concerns for many. Below, I will address these questions from nine aspects.

First, which antihypertensive medication is truly effective? Generally speaking, certain calcium channel blockers (e.g., "dihydropyridines") are slightly more potent than certain angiotensin II receptor blockers (e.g., "sartans"), while beta-blockers (e.g., "lols") are the weakest. However, the choice should be tailored to individual circumstances. For example, younger individuals with high sympathetic nervous system activity may benefit more from beta-blockers, making them the most effective option in such cases. Therefore, any medication that can lower blood pressure to the normal range is considered effective.

Second, do antihypertensive medications need to be changed frequently? As long as blood pressure remains stable, there is no need to switch medications.

Third, how much can one antihypertensive pill lower blood pressure? This depends on the individual's blood pressure level. Generally, the higher the blood pressure, the greater the reduction. For someone with a blood pressure of 180 mmHg, it might drop by 20 mmHg, while for someone with a blood pressure of 140 mmHg, it might only drop by 5–10 mmHg.

Fourth, are antihypertensive medications addictive? I can confidently say they are not. Your blood pressure will return to its original level once you stop taking the medication.

Fifth, if the systolic blood pressure is too high while the diastolic blood pressure is only around 60 mmHg, will taking antihypertensive medication cause the diastolic pressure to drop excessively? The human body has its own regulatory mechanisms. Generally, antihypertensive medications are more effective at lowering systolic blood pressure. This is also why it is challenging to lower blood pressure in individuals with isolated diastolic hypertension. However, if the diastolic pressure is low but medication is still necessary, it should be taken as prescribed.

Sixth, can antihypertensive medication be stopped once blood pressure returns to normal? If your blood pressure was below 160 mmHg before starting medication, and you have recently focused on weight loss, exercise, and reducing salt intake over the past three months, with your current blood pressure around 120 mmHg, you may consider discontinuing the medication. However, blood pressure should be monitored regularly after stopping. If your blood pressure was very high before starting medication, it is best not to attempt discontinuation.

Seventh, should antihypertensive medication be taken before or after meals? In fact, either is acceptable. However, some patients may experience hypotension after meals, so taking medication after eating is preferable, as blood pressure will not be too low when the drug takes effect. Always follow the instructions on the medication label for any special precautions.

Eighth, should antihypertensive medication be taken in the morning or afternoon? It is advisable to check your ambulatory blood pressure. If your blood pressure is higher at night, take the medication in the afternoon. If it is higher during the day, take it in the morning. Adjust according to your individual situation.

Ninth, do antihypertensive medications harm liver and kidney function? While many medications can potentially affect liver and kidney function, antihypertensive drugs are relatively safe. Many people have taken them for decades without issues. When used appropriately under medical guidance, they generally do not harm liver or kidney function.